Genetic Variation in Neisseria meningitidis Does Not Influence Disease Severity in Meningococcal Meningitis

Genetic Variation in Neisseria meningitidis Does Not Influence Disease Severity in Meningococcal Meningitis

Neisseria meningitidis causes sepsis and meningitis in humans. It has been suggested that pathogen genetic variation determines variance in disease severity. Here we report results of a genome-wide association study of 486 N. meningitidis genomes from meningococcal meningitis patients and their asso...

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Hlavní autoři: Philip H. C. Kremer, John A. Lees, Bart Ferwerda, Arie van de Ende, Matthijs C. Brouwer, Stephen D. Bentley, Diederik van de Beek
Médium: Článek
Jazyk:English
Vydáno: Frontiers Media S.A. 2020-11-01
Edice:Frontiers in Medicine
Témata:
severity
genome-wide association study
genome sequencing
Neisseria meningitidis
thrombocytes
On-line přístup:https://www.frontiersin.org/articles/10.3389/fmed.2020.594769/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2020.594769/full

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