Genetic Variation in Neisseria meningitidis Does Not Influence Disease Severity in Meningococcal Meningitis

Neisseria meningitidis causes sepsis and meningitis in humans. It has been suggested that pathogen genetic variation determines variance in disease severity. Here we report results of a genome-wide association study of 486 N. meningitidis genomes from meningococcal meningitis patients and their asso...

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Main Authors: Philip H. C. Kremer, John A. Lees, Bart Ferwerda, Arie van de Ende, Matthijs C. Brouwer, Stephen D. Bentley, Diederik van de Beek
格式: Article
語言:English
出版: Frontiers Media S.A. 2020-11-01
叢編:Frontiers in Medicine
主題:
在線閱讀:https://www.frontiersin.org/articles/10.3389/fmed.2020.594769/full