Etiology-Specific Analysis of Hepatocellular Carcinoma Transcriptome Reveals Genetic Dysregulation in Pathways Implicated in Immunotherapy Efficacy

Etiology-Specific Analysis of Hepatocellular Carcinoma Transcriptome Reveals Genetic Dysregulation in Pathways Implicated in Immunotherapy Efficacy

Immunotherapy has emerged in recent years as arguably the most effective treatment for advanced hepatocellular carcinoma (HCC), but the failure of a large percentage of patients to respond to immunotherapy remains as the ultimate obstacle to successful treatment. Etiology-associated dysregulation of...

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Bibliographic Details
Main Authors: Wei Tse Li, Angela E. Zou, Christine O. Honda, Hao Zheng, Xiao Qi Wang, Tatiana Kisseleva, Eric Y. Chang, Weg M. Ongkeko
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cancers
Subjects:
cancer immunotherapy
TCGA
mutations
copy number variations
microRNAs
Online Access:https://www.mdpi.com/2072-6694/11/9/1273

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https://www.mdpi.com/2072-6694/11/9/1273

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