Recombinant Receptor Binding Domain Protein Induces Partial Protective Immunity in Rhesus Macaques Against Middle East Respiratory Syndrome Coronavirus Challenge

Recombinant Receptor Binding Domain Protein Induces Partial Protective Immunity in Rhesus Macaques Against Middle East Respiratory Syndrome Coronavirus Challenge

Background: Development an effective vaccine against Middle East respiratory syndrome coronavirus (MERS-CoV) is urgent and limited information is available on vaccination in nonhuman primate (NHP) model. We herein report of evaluating a recombinant receptor-binding domain (rRBD) protein vaccine in a...

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Bibliographic Details
Main Authors: Jiaming Lan, Yanfeng Yao, Yao Deng, Hong Chen, Guangwen Lu, Wen Wang, Linlin Bao, Wei Deng, Qiang Wei, George F. Gao, Chuan Qin, Wenjie Tan
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:EBioMedicine
Subjects:
Immunity
RBD
MERS-CoV
Vaccine
Protection
Rhesus macaque
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396415301158

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http://www.sciencedirect.com/science/article/pii/S2352396415301158

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