Progressive Decline in Gray and White Matter Integrity in de novo Parkinson’s Disease: An Analysis of Longitudinal Parkinson Progression Markers Initiative Diffusion Tensor Imaging Data

Background: Progressive neuronal loss in neurodegenerative diseases such as Parkinson’s disease (PD) is associated with progressive degeneration of associated white matter tracts as measured by diffusion tensor imaging (DTI). These findings may have diagnostic and functional implications but their v...

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Bibliographic Details
Main Authors: Kirsten I. Taylor, Fabio Sambataro, Frank Boess, Alessandro Bertolino, Juergen Dukart
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2018.00318/full