Late Onset of Estrogen Therapy Impairs Carotid Function of Senescent Females in Association with Altered Prostanoid Balance and Upregulation of the Variant ERα36

Late Onset of Estrogen Therapy Impairs Carotid Function of Senescent Females in Association with Altered Prostanoid Balance and Upregulation of the Variant ERα36

Recent analysis of clinical trials on estrogen therapy proposes the existence of a therapeutic window of opportunity for the cardiovascular benefits of estrogens, which depend on women’s age and the onset of therapy initiation. In this study, we aimed to determine how vascular senescence a...

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Bibliographic Details
Main Authors: Tiago Januário Costa, Francesc Jiménez-Altayó, Cinthya Echem, Eliana Hiromi Akamine, Rita Tostes, Elisabet Vila, Ana Paula Dantas, Maria Helena Catelli de Carvalho
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cells
Subjects:
estrogen
aging
estrogen receptor variants
cerebrovascular function
menopause
hormone replacement therapy
Online Access:https://www.mdpi.com/2073-4409/8/10/1217

Internet

https://www.mdpi.com/2073-4409/8/10/1217

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