Dysregulated T-cell homeostasis and decreased CD30+ Treg proliferating in aplastic anemia

Dysregulated T-cell homeostasis and decreased CD30+ Treg proliferating in aplastic anemia

Aplastic anemia (AA) is an autoimmune hematopoietic disease mediated by autoreactive T cells leading to bone marrow failure. However, the precise role of autoreactive T cells in the development of AA is not fully understood, hindering the advancement of therapeutic and diagnostic strategies. In this...

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Bibliographic Details
Main Authors: Nannan Sun, Mengmeng Zhang, Jingjing Kong, Jin Li, Yong Dong, Xiaoqian Wang, Liyan Fu, Yiwei Zhou, Yaoyao Chen, Yingmei Li, Xianlei Sun, Rongqun Guo
Format: Article
Language:English
Published: Elsevier 2024-08-01
Series:Heliyon
Subjects:
Single-cell RNA sequencing
Aplastic anemia
CD30 (TNFRSF8)
T cell homeostasis
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024118063

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http://www.sciencedirect.com/science/article/pii/S2405844024118063

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