CXCL10 is a novel anti‐angiogenic factor downstream of p53 in cardiomyocytes

CXCL10 is a novel anti‐angiogenic factor downstream of p53 in cardiomyocytes

Abstract Tumor suppressor protein p53 plays crucial roles in the onset of heart failure. p53 activation results in cardiac dysfunction, at least partially by suppressing angiogenesis. Though p53 has been reported to reduce VEGF production by inhibiting hypoxia‐inducible factor, the anti‐angiogenic p...

Full description

Bibliographic Details
Main Authors: Tri Wahyuni, Shota Tanaka, Ryuta Igarashi, Yoshiaki Miyake, Ayaha Yamamoto, Shota Mori, Yusuke Kametani, Masashi Tomimatsu, Shota Suzuki, Kosei Yokota, Yoshiaki Okada, Makiko Maeda, Masanori Obana, Yasushi Fujio
Format: Article
Language:English
Published: Wiley 2022-05-01
Series:Physiological Reports
Subjects:
angiogenesis
cardiomyocyte
CXCL10
hypoxia
p53
Online Access:https://doi.org/10.14814/phy2.15304

Internet

https://doi.org/10.14814/phy2.15304

Similar Items