The Impact of Sub-Millisecond Damage Fixation Kinetics on the In Vitro Sparing Effect at Ultra-High Dose Rate in UNIVERSE

The Impact of Sub-Millisecond Damage Fixation Kinetics on the In Vitro Sparing Effect at Ultra-High Dose Rate in UNIVERSE

The impact of the exact temporal pulse structure on the potential cell and tissue sparing of ultra-high dose-rate irradiation applied in FLASH studies has gained increasing attention. A previous version of our biophysical mechanistic model (UNIVERSE: UNIfied and VERSatile bio response Engine), based...

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Bibliographic Details
Main Authors: Hans Liew, Stewart Mein, Thomas Tessonnier, Amir Abdollahi, Jürgen Debus, Ivana Dokic, Andrea Mairani
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
ionizing radiation
FLASH
UNIVERSE
modeling
ultra-high dose rate
temporal pulse structure
Online Access:https://www.mdpi.com/1422-0067/23/6/2954

Internet

https://www.mdpi.com/1422-0067/23/6/2954

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