Development of Acridone Derivatives: Targeting <i>c-MYC</i> Transcription in Triple-Negative Breast Cancer with Inhibitory Potential

Development of Acridone Derivatives: Targeting <i>c-MYC</i> Transcription in Triple-Negative Breast Cancer with Inhibitory Potential

Breast cancer, especially the aggressive triple-negative subtype, poses a serious health threat to women. Unfortunately, effective targets are lacking, leading to a grim prognosis. Research highlights the crucial role of <i>c-MYC</i> overexpression in this form of cancer. Current inhibit...

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Bibliographic Details
Main Authors: Jing-Wei Liang, Zhi-Chao Gao, Lu-Lu Yang, Wei Zhang, Ming-Zhe Chen, Fan-Hao Meng
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Antioxidants
Subjects:
acridone derivatives
<i>c-MYC</i>
G-quadruplex
TNBC
ROS
Online Access:https://www.mdpi.com/2076-3921/13/1/11

Internet

https://www.mdpi.com/2076-3921/13/1/11

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