The Role of Toll-Like Receptor 2 and 4 Innate Immunity Pathways in Intracortical Microelectrode-Induced Neuroinflammation

The Role of Toll-Like Receptor 2 and 4 Innate Immunity Pathways in Intracortical Microelectrode-Induced Neuroinflammation

We have recently demonstrated that partial inhibition of the cluster of differentiation 14 (CD14) innate immunity co-receptor pathway improves the long-term performance of intracortical microelectrodes better than complete inhibition. We hypothesized that partial activation of the CD14 pathway was c...

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Bibliographic Details
Main Authors: John K. Hermann, Shushen Lin, Arielle Soffer, Chun Wong, Vishnupriya Srivastava, Jeremy Chang, Smrithi Sunil, Shruti Sudhakar, William H. Tomaszewski, Grace Protasiewicz, Stephen M. Selkirk, Robert H. Miller, Jeffrey R. Capadona
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
BCI
intracortical microelectrode
neuroinflammation
innate immunity
Toll-like receptors
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2018.00113/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2018.00113/full

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