Effects of the Radix Ginseng and Semen Ziziphi Spinosae drug pair on the GLU/GABA-GLN metabolic cycle and the intestinal microflora of insomniac rats based on the brain–gut axis

Effects of the Radix Ginseng and Semen Ziziphi Spinosae drug pair on the GLU/GABA-GLN metabolic cycle and the intestinal microflora of insomniac rats based on the brain–gut axis

Introduction: To explore the mechanism of action of appling Radix Ginseng and Semen Ziziphi Spinosae Drug pair (R-S) in the treatment of insomnia by investigating the effect of R-S on GLU/GABA-GLN metabolic cycle and intestinal microflora of rats with insomnia.Methods: Rats were intraperitoneally in...

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Bibliographic Details
Main Authors: Tie Qiao, Yuan Wang, Ke Liang, Bingyuan Zheng, Jin Ma, Fangxiao Li, Chi Liu, Mingdan Zhu, Meng Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Pharmacology
Subjects:
Radix Ginseng–Semen Ziziphi Spinosae
drug pair
insomnia
GLU/GABA-GLN metabolic cycle
intestinal microflora
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1094507/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.1094507/full

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