Antipsychotic Drug Aripiprazole Protects Liver Cells from Oxidative Stress

Antipsychotic Drug Aripiprazole Protects Liver Cells from Oxidative Stress

Antipsychotics used to treat schizophrenia can cause drug-induced liver injury (DILI), according to the Roussel Uclaf Causality Assessment Method. The role of oxidative stress in triggering injury in these DILI cases is unknown. We repeatedly administrated two second-generation antipsychotics, aripi...

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Bibliographic Details
Main Authors: Barbara Kramar, Tinkara Pirc Marolt, Maria Monsalve, Dušan Šuput, Irina Milisav
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:International Journal of Molecular Sciences
Subjects:
aripiprazole
olanzapine
oxidative stress
chemical and drug induced liver injury
second-generation antipsychotics
stress response
Online Access:https://www.mdpi.com/1422-0067/23/15/8292

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https://www.mdpi.com/1422-0067/23/15/8292

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