Repurposing live attenuated trivalent MMR vaccine as cost-effective cancer immunotherapy

Repurposing live attenuated trivalent MMR vaccine as cost-effective cancer immunotherapy

It has long been known that oncolytic viruses wield their therapeutic capability by priming an inflammatory state within the tumor and activating the tumor immune microenvironment, resulting in a multifaceted antitumor immune response. Vaccine-derived viruses, such as measles and mumps, have demonst...

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Bibliographic Details
Main Authors: Yuguo Zhang, Musa Gabere, Mika A. Taylor, Camila C. Simoes, Chelsae Dumbauld, Oumar Barro, Mulu Z. Tesfay, Alicia L. Graham, Khandoker Usran Ferdous, Alena V. Savenka, Jean Christopher Chamcheu, Charity L. Washam, Duah Alkam, Allen Gies, Stephanie D. Byrum, Matteo Conti, Steven R. Post, Thomas Kelly, Mitesh J. Borad, Martin J. Cannon, Alexei Basnakian, Bolni M. Nagalo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Oncology
Subjects:
live attenuated vaccine
hepatocellular carcinoma
colorectal cancer
measles
mumps
rubella (MMR) vaccine
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1042250/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.1042250/full

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