Failure of the vascular hypothesis of multiple sclerosis in a rat model of chronic cerebrospinal venous insufficiency

Failure of the vascular hypothesis of multiple sclerosis in a rat model of chronic cerebrospinal venous insufficiency

Chronic cerebrospinal venous insufficiency (CCSVI) is a series of stenotic malformations in the cerebrospinal venous outflow routes, which is postulated to cause multiple sclerosis (MS). The hypotheses assumed that CCSVI leads to iron deposition which triggers inflammation and demyelination in MS. I...

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Bibliographic Details
Main Authors: Maha M.A. Zakaria, Shahira Y. Mikhael, Azza K. Abu Hussein, Rania A. Salah El-din, Hany W. Abd El-Malak, Iman H. Hewedi, Hany S. Nadim
Format: Article
Language:English
Published: Termedia Publishing House 2017-03-01
Series:Folia Neuropathologica
Subjects:
<i>CCSVI
multiple sclerosis
animal model
jugular veins
iron overload</i>
Online Access:https://www.termedia.pl/Failure-of-the-vascular-hypothesis-of-multiple-sclerosis-in-a-rat-model-of-chronic-cerebrospinal-venous-insufficiency,20,29687,1,1.html

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https://www.termedia.pl/Failure-of-the-vascular-hypothesis-of-multiple-sclerosis-in-a-rat-model-of-chronic-cerebrospinal-venous-insufficiency,20,29687,1,1.html

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