Input-specific modulation of murine nucleus accumbens differentially regulates hedonic feeding

Hedonic feeding occurs in the absence of metabolic need and plays a critical role in the excessive feeding that underlies obesity. The authors show that optogenetic manipulation of NAc inputs from the prefrontal cortex versus inputs from the anterior paraventricular nucleus of the thalamus has oppos...

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Bibliographic Details
Main Authors: Daniel J. Christoffel, Jessica J. Walsh, Boris D. Heifets, Paul Hoerbelt, Sophie Neuner, Gordon Sun, Vinod K. Ravikumar, Hemmings Wu, Casey H. Halpern, Robert C. Malenka
Format: Article
Language:English
Published: Nature Portfolio 2021-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-22430-7