Absence of association between Pfnfs1 mutation and in vitro susceptibility to lumefantrine in Plasmodium falciparum

Absence of association between Pfnfs1 mutation and in vitro susceptibility to lumefantrine in Plasmodium falciparum

Artemether-lumefantrine (AL) is the most widely used antimalarial drug for treating uncomplicated falciparum malaria. This study evaluated whether the K65Q mutation in the Plasmodium falciparum cysteine desulfurase IscS (Pfnfs1) gene was associated with alternated susceptibility to lumefantrine usin...

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Bibliographic Details
Main Authors: Weilin Zeng, Wei Zhao, Hao Wei, Yucheng Qin, Zheng Xiang, Yanrui Wu, Xi Chen, Yanmei Zhang, Hui Zhao, Mengxi Duan, Wenya Zhu, Kemin Sun, Yiman Wu, Tao Liang, Ye Mou, Cheng Liu, Xiuya Tang, Yaming Huang, Liwang Cui, Zhaoqing Yang
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Subjects:
Plasmodium falciparum
In vitro susceptibility
Lumefantrine
Pfnfs1 gene
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320724000137

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http://www.sciencedirect.com/science/article/pii/S2211320724000137

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