Live cell imaging reveals 3′-UTR dependent mRNA sorting to synapses

Live cell imaging reveals 3′-UTR dependent mRNA sorting to synapses

Asymmetric subcellular mRNA distribution is important for local translation of neuronal mRNAs. Here the authors employed MS2 live-cell imaging and showed that the reporter mRNA containing the 3’ UTR of Rgs4 shows an anterograde transport bias, dependent on neuronal activity and the protein Staufen2,...

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Bibliographic Details
Main Authors: Karl E. Bauer, Inmaculada Segura, Imre Gaspar, Volker Scheuss, Christin Illig, Georg Ammer, Saskia Hutten, Eugénia Basyuk, Sandra M. Fernández-Moya, Janina Ehses, Edouard Bertrand, Michael A. Kiebler
Format: Article
Language:English
Published: Nature Portfolio 2019-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11123-x

Internet

https://doi.org/10.1038/s41467-019-11123-x

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