Nuciferine Effectively Protects Mice against Acetaminophen-Induced Liver Injury

Nuciferine Effectively Protects Mice against Acetaminophen-Induced Liver Injury

Acetaminophen (APAP) overdose still poses a major clinical challenge and is a leading cause of acute liver injury (ALI). N-acetylcysteine (NAC) is the only approved antidote to treat APAP toxicity while NAC therapy can trigger side effects including severe vomiting and even shock. Thus, new insights...

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Bibliographic Details
Main Authors: Zixiong Zhou, Jing Qi, Yajiao Wu, Chutao Li, Wenqiang Bao, Xiaohuang Lin, An Zhu
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Antioxidants
Subjects:
acetaminophen
acute liver injury
nuciferine
oxidative stress
autophagy
anti-inflammatory responses
Online Access:https://www.mdpi.com/2076-3921/12/4/949

Internet

https://www.mdpi.com/2076-3921/12/4/949

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