Low-dose administration of prednisone has a good effect on the treatment of prolonged hematologic toxicity post-CD19 CAR-T cell therapy

Low-dose administration of prednisone has a good effect on the treatment of prolonged hematologic toxicity post-CD19 CAR-T cell therapy

IntroductionHematologic toxicity (HT) is a joint adverse event after CAR-T cells infusion. Some patients experience prolonged hematologic toxicity (PHT), which is challenging to treat.MethodsWe collected clinical data from patients with relapsed refractory B-ALL treated with CD19 CAR-T cells. Patien...

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Bibliographic Details
Main Authors: Jiaxi Wang, Meng Zhang, Hairong Lyu, Ruiting Guo, Xia Xiao, Xue Bai, Yedi Pu, Juanxia Meng, Qing Li, Ting Yuan, Wenyi Lu, Mingfeng Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
CAR-T cells
acute lymphocytic leukemia
prolonged hematologic toxicity
prednisone
hematopoietic recovery
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1139559/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1139559/full

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