Fusion sequencing via terminator‐assisted synthesis (FTAS‐seq) identifies TMPRSS2 fusion partners in prostate cancer

Fusion sequencing via terminator‐assisted synthesis (FTAS‐seq) identifies TMPRSS2 fusion partners in prostate cancer

Genetic rearrangements that fuse an androgen‐regulated promoter area with a protein‐coding portion of an originally androgen‐unaffected gene are frequent in prostate cancer, with the fusion between transmembrane serine protease 2 (TMPRSS2) and ETS transcription factor ERG (ERG) (TMPRSS2‐ERG fusion)...

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Bibliographic Details
Main Authors: Ugnė Drazdauskienė, Žana Kapustina, Justina Medžiūnė, Varvara Dubovskaja, Rasa Sabaliauskaitė, Sonata Jarmalaitė, Arvydas Lubys
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:Molecular Oncology
Subjects:
fusion transcripts
prostate cancer
RNA sequencing
TMPRSS2
transcriptomics
Online Access:https://doi.org/10.1002/1878-0261.13428

Internet

https://doi.org/10.1002/1878-0261.13428

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