Age-dependent decrease in glutamine synthetase expression in the hippocampal astroglia of the triple transgenic Alzheimer's disease mouse model: mechanism for deficient glutamatergic transmission?

<p>Abstract</p> <p>Astrocytes are fundamental for brain homeostasis and the progression and outcome of many neuropathologies including Alzheimer's disease (AD). In the triple transgenic mouse model of AD (3xTg-AD) generalised hippocampal astroglia atrophy precedes a restricted...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Verkhratsky Alexei, Noristani Harun N, Olabarria Markel, Rodríguez José J
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: BMC 2011-07-01
Σειρά:Molecular Neurodegeneration
Θέματα:
Διαθέσιμο Online:http://www.molecularneurodegeneration.com/content/6/1/55