Age-dependent decrease in glutamine synthetase expression in the hippocampal astroglia of the triple transgenic Alzheimer's disease mouse model: mechanism for deficient glutamatergic transmission?
<p>Abstract</p> <p>Astrocytes are fundamental for brain homeostasis and the progression and outcome of many neuropathologies including Alzheimer's disease (AD). In the triple transgenic mouse model of AD (3xTg-AD) generalised hippocampal astroglia atrophy precedes a restricted...
Main Authors: | Verkhratsky Alexei, Noristani Harun N, Olabarria Markel, Rodríguez José J |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-07-01
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Series: | Molecular Neurodegeneration |
Subjects: | |
Online Access: | http://www.molecularneurodegeneration.com/content/6/1/55 |
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