Organocatalytic diastereo- and atroposelective construction of N–N axially chiral pyrroles and indoles

Abstract The construction of N–N axially chiral motifs is an important research topic, owing to their wide occurrence in natural products, pharmaceuticals and chiral ligands. One efficient method is the atroposelective dihydropyrimidin-4-one formation. We present herein a direct catalytic synthesis...

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Bibliographic Details
Main Authors: Shao-Jie Wang, Xia Wang, Xiaolan Xin, Shulei Zhang, Hui Yang, Ming Wah Wong, Shenci Lu
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-44743-z