A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma

A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma

Summary: Glioblastoma (GBM) is a malignant brain tumor with few therapeutic options. The disease presents with a complex spectrum of genomic aberrations, but the pharmacological consequences of these aberrations are partly unknown. Here, we report an integrated pharmacogenomic analysis of 100 patien...

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Bibliographic Details
Main Authors: Patrik Johansson, Cecilia Krona, Soumi Kundu, Milena Doroszko, Sathishkumar Baskaran, Linnéa Schmidt, Claire Vinel, Elin Almstedt, Ramy Elgendy, Ludmila Elfineh, Caroline Gallant, Sara Lundsten, Fernando J. Ferrer Gago, Aleksi Hakkarainen, Petra Sipilä, Maria Häggblad, Ulf Martens, Bo Lundgren, Melanie M. Frigault, David P. Lane, Fredrik J. Swartling, Lene Uhrbom, Marika Nestor, Silvia Marino, Sven Nelander
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Cell Reports
Subjects:
biobank
combination therapy
data integration
glioblastoma
multi-omics
p53 reactivators
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720308780

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http://www.sciencedirect.com/science/article/pii/S2211124720308780

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