RhoGDIβ-induced hypertrophic growth in H9c2 cells is negatively regulated by ZAK

<p>Abstract</p> <p>We found that overexpression of RhoGDIβ, a Rho GDP dissociation inhibitor, induced hypertrophic growth and suppressed cell cycle progression in a cultured cardiomyoblast cell line. Knockdown of RhoGDIβ expression by RNA interference blocked hypertrophic growth. W...

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Bibliographic Details
Main Authors: Huang Chih-Yang, Yang Li-Chiu, Liu Kuan-Yu, Liao Pao-Hsin, Chou Janet, Chou Ming-Yung, Lin Wei-Wen, Yang Jaw-Ji
Format: Article
Language:English
Published: BMC 2009-01-01
Series:Journal of Biomedical Science
Online Access:http://www.jbiomedsci.com/content/16/1/11