No Difference in the Prevalence of HIV-1 <i>gag</i> Cytotoxic T-Lymphocyte-Associated Escape Mutations in Viral Sequences from Early and Late Parts of the HIV-1 Subtype C Pandemic in Botswana

No Difference in the Prevalence of HIV-1 <i>gag</i> Cytotoxic T-Lymphocyte-Associated Escape Mutations in Viral Sequences from Early and Late Parts of the HIV-1 Subtype C Pandemic in Botswana

HIV is known to accumulate escape mutations in the <i>gag</i> gene in response to the immune response from cytotoxic T lymphocytes (CTLs). These mutations can occur within an individual as well as at a population level. The population of Botswana exhibits a high prevalence of HLA*B57 and...

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Bibliographic Details
Main Authors: Baitshepi Mokaleng, Wonderful Tatenda Choga, Ontlametse Thato Bareng, Dorcas Maruapula, Doreen Ditshwanelo, Nametso Kelentse, Patrick Mokgethi, Natasha Onalenna Moraka, Modisa Sekhamo Motswaledi, Leabaneng Tawe, Catherine Kegakilwe Koofhethile, Sikhulile Moyo, Matshediso Zachariah, Simani Gaseitsiwe
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Vaccines
Subjects:
HLA-associated
<i>gag</i>
recent infections
CTL escape mutations
HIV evolution
Botswana
Online Access:https://www.mdpi.com/2076-393X/11/5/1000

Internet

https://www.mdpi.com/2076-393X/11/5/1000

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