Myogenic tissue nanotransfection improves muscle torque recovery following volumetric muscle loss
Abstract This work rests on our non-viral tissue nanotransfection (TNT) platform to deliver MyoD (TNTMyoD) to injured tissue in vivo. TNTMyoD was performed on skin and successfully induced expression of myogenic factors. TNTMyoD was then used as a therapy 7 days following volumetric muscle loss (VML...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-10-01
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Series: | npj Regenerative Medicine |
Online Access: | https://doi.org/10.1038/s41536-022-00259-y |