Microcirculatory perfusion disturbances following cardiac surgery with cardiopulmonary bypass are associated with in vitro endothelial hyperpermeability and increased angiopoietin-2 levels

Microcirculatory perfusion disturbances following cardiac surgery with cardiopulmonary bypass are associated with in vitro endothelial hyperpermeability and increased angiopoietin-2 levels

Abstract Background Endothelial hyperpermeability following cardiopulmonary bypass (CPB) contributes to microcirculatory perfusion disturbances and postoperative complications after cardiac surgery. We investigated the postoperative course of renal and pulmonary endothelial barrier function and the...

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Bibliographic Details
Main Authors: Nicole A. M. Dekker, Anoek L. I. van Leeuwen, Willem W. J. van Strien, Jisca Majolée, Robert Szulcek, Alexander B. A. Vonk, Peter L. Hordijk, Christa Boer, Charissa E. van den Brom
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Critical Care
Subjects:
Cardiopulmonary bypass
Angiopoietin-2
Capillary permeability
Microcirculation
Endothelium
Online Access:http://link.springer.com/article/10.1186/s13054-019-2418-5

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http://link.springer.com/article/10.1186/s13054-019-2418-5

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