The rearing environment persistently modulates mouse phenotypes from the molecular to the behavioural level.

The phenotype of an organism results from its genotype and the influence of the environment throughout development. Even when using animals of the same genotype, independent studies may test animals of different phenotypes, resulting in poor replicability due to genotype-by-environment interactions....

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Bibliographic Details
Main Authors: Ivana Jaric, Bernhard Voelkl, Melanie Clerc, Marc W Schmid, Janja Novak, Marianna Rosso, Reto Rufener, Vanessa Tabea von Kortzfleisch, S Helene Richter, Manuela Buettner, André Bleich, Irmgard Amrein, David P Wolfer, Chadi Touma, Shinichi Sunagawa, Hanno Würbel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-10-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001837