Impact of data preprocessing on cell-type clustering based on single-cell RNA-seq data

Impact of data preprocessing on cell-type clustering based on single-cell RNA-seq data

Abstract Background Advances in single-cell RNA-seq technology have led to great opportunities for the quantitative characterization of cell types, and many clustering algorithms have been developed based on single-cell gene expression. However, we found that different data preprocessing methods sho...

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Bibliographic Details
Main Authors: Chunxiang Wang, Xin Gao, Juntao Liu
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Bioinformatics
Subjects:
Preprocessing method
Single-cell RNA-seq data
Gene expression data
Single-cell clustering
SC3
Online Access:http://link.springer.com/article/10.1186/s12859-020-03797-8

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http://link.springer.com/article/10.1186/s12859-020-03797-8

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