Mitochondrial Unfolded Protein Responses in White Adipose Tissue: Lipoatrophy, Whole-Body Metabolism and Lifespan

The mitochondrial unfolded protein response (UPR<sup>mt</sup>) is a stress response mediated by the expression of genes such as chaperones, proteases, and mitokines to maintain mitochondrial proteostasis. Certain genetically modified mice, which defect mitochondrial proteins specifically...

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Bibliographic Details
Main Authors: Masaki Kobayashi, Yuichiro Nezu, Ryoma Tagawa, Yoshikazu Higami
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/6/2854