Overload Induced Heat Shock Proteins (HSPs), MAPK and miRNA (miR-1 and miR133a) Response in Insulin-Resistant Skeletal Muscle

Overload Induced Heat Shock Proteins (HSPs), MAPK and miRNA (miR-1 and miR133a) Response in Insulin-Resistant Skeletal Muscle

Background: Insulin resistance (IR) may decrease muscle adaptability. Heat shock proteins (HSPs), mitogen-activated protein kinases (MAPKs), and miRNA are thought to play a role in muscle hypertrophy but it is unclear if IR may affect their regulation. Methods: Soleus muscles of lean Zucker (LZ) and...

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Bibliographic Details
Main Authors: Anjaiah Katta, Srinivasarao Thulluri, Nandini D.P.K. Manne, Hari S. Addagarla, Ravikumar Arvapalli, Siva K. Nalabotu, Muralikrishna Gadde, Kevin M. Rice, Eric R. Blough
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-02-01
Series:Cellular Physiology and Biochemistry
Subjects:
Heat shock proteins
Mitogen-activated protein kinases
miRNA
Insulin resistance
Muscle overload
Online Access:http://www.karger.com/Article/FullText/343363

Internet

http://www.karger.com/Article/FullText/343363

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