C1 esterase inhibitor reduces lower extremity ischemia/reperfusion injury and associated lung damage.

BACKGROUND:Ischemia/reperfusion injury of lower extremities and associated lung damage may result from thrombotic occlusion, embolism, trauma, or surgical intervention with prolonged ischemia and subsequent restoration of blood flow. This clinical entity is characterized by high morbidity and mortal...

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Bibliographic Details
Main Authors: Claudia Duehrkop, Yara Banz, Rolf Spirig, Sylvia Miescher, Marc W Nolte, Martin Spycher, Richard A G Smith, Steven H Sacks, Robert Rieben
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3753343?pdf=render