Sinomenine Confers Protection Against Myocardial Ischemia Reperfusion Injury by Preventing Oxidative Stress, Cellular Apoptosis, and Inflammation

Sinomenine Confers Protection Against Myocardial Ischemia Reperfusion Injury by Preventing Oxidative Stress, Cellular Apoptosis, and Inflammation

Sinomenine (SIN), an alkaloid extracted from the root of S. acutum. sinomenine, has been shown to have antiarrhythmic, antioxidant, and anti-inflammatory effects in myocardial ischemia-reperfusion injury (MIRI) ex vivo. In this study, we investigated the cardioprotective effects of SIN in an in vivo...

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Bibliographic Details
Main Authors: Boyu Xia, Qi Li, Jingjing Wu, Xiaomei Yuan, Fei Wang, Xu Lu, Chao Huang, Koulong Zheng, Rongrong Yang, Le Yin, Kun Liu, Qingsheng You
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Pharmacology
Subjects:
sinomenine
ischemia reperfusion injury
oxidative stress
inflammation
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.922484/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.922484/full

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