Development and laboratory evaluation of a competitive ELISA for serodiagnosis of Nipah and Hendra virus infection using recombinant Nipah glycoproteins and a monoclonal antibody

Development and laboratory evaluation of a competitive ELISA for serodiagnosis of Nipah and Hendra virus infection using recombinant Nipah glycoproteins and a monoclonal antibody

IntroductionNipah virus (NiV) and Hendra virus (HeV), of the genus Henipavirus, family Paramyxoviridae, are classified as Risk Group 4 (RG4) pathogens that cause respiratory disease in pigs and acute/febrile encephalitis in humans with high mortality.MethodsA competitive enzyme–linked immunosorbent...

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Bibliographic Details
Main Authors: Wenjun Zhu, Bradley Pickering, Greg Smith, Mathieu Pinette, Thang Truong, Shawn Babiuk, Darwyn Kobasa, Logan Banadyga, Ming Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Veterinary Science
Subjects:
Nipah virus
Hendra virus
Henipavirus
recombinant Nipah virus glycoprotein
monoclonal antibody
competitive ELISA
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2023.1120367/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2023.1120367/full

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