Gi Protein Modulation of the Potassium Channel TASK-2 Mediates Vesicle Osmotic Swelling to Facilitate the Fusion of Aquaporin-2 Water Channel Containing Vesicles

Gi Protein Modulation of the Potassium Channel TASK-2 Mediates Vesicle Osmotic Swelling to Facilitate the Fusion of Aquaporin-2 Water Channel Containing Vesicles

Vesicle fusion is a fundamental cell biological process similar from yeasts to humans. For secretory vesicles, swelling is considered a step required for the expulsion of intravesicular content. Here this concept is revisited providing evidence that it may instead represent a general mechanism. We r...

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Bibliographic Details
Main Authors: Mariangela Centrone, Maria Penelope De Santo, Isabella Nicotera, Cristina Labate, Marianna Ranieri, Annarita Di Mise, Maria Grazia Mola, Maria Mastrodonato, Rosangela Elliani, Riccardo Barberi, Vincenzo Formoso, Grazia Tamma, Giovanna Valenti
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Cells
Subjects:
Gi protein
TASK-2
Aquaporin-2
exocytosis
swelling
Online Access:https://www.mdpi.com/2073-4409/7/12/276

Internet

https://www.mdpi.com/2073-4409/7/12/276

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