Antimicrobial Resistance in <i>Salmonella</i> Isolated from Food Workers and Chicken Products in Japan
<i>Salmonella</i> is an enteric bacterial pathogen that causes foodborne illness in humans. Third-generation cephalosporin (TGC) resistance in <i>Salmonella</i> remains a global concern. Food workers may represent a reservoir of <i>Salmonella</i>, thus potentially...
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| Format: | Article |
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MDPI AG
2021-12-01
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| Series: | Antibiotics |
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| Online Access: | https://www.mdpi.com/2079-6382/10/12/1541 |
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| author | Yoshimasa Sasaki Hiromi Kakizawa Youichi Baba Takeshi Ito Yukari Haremaki Masaru Yonemichi Tetsuya Ikeda Makoto Kuroda Kenji Ohya Yukiko Hara-Kudo Tetsuo Asai Hiroshi Asakura |
| author_facet | Yoshimasa Sasaki Hiromi Kakizawa Youichi Baba Takeshi Ito Yukari Haremaki Masaru Yonemichi Tetsuya Ikeda Makoto Kuroda Kenji Ohya Yukiko Hara-Kudo Tetsuo Asai Hiroshi Asakura |
| author_sort | Yoshimasa Sasaki |
| collection | DOAJ |
| description | <i>Salmonella</i> is an enteric bacterial pathogen that causes foodborne illness in humans. Third-generation cephalosporin (TGC) resistance in <i>Salmonella</i> remains a global concern. Food workers may represent a reservoir of <i>Salmonella</i>, thus potentially contaminating food products. Therefore, we aimed to investigate the prevalence of <i>Salmonella</i> in food workers and characterize the isolates by serotyping and antimicrobial susceptibility testing. <i>Salmonella</i> was isolated from 583 (0.079%) of 740,635 stool samples collected from food workers between January and December 2018, and then serotyped into 76 <i>Salmonella enterica</i> serovars and 22 untypeable <i>Salmonella</i> strains. High rates of antimicrobial resistance were observed for streptomycin (51.1%), tetracycline (33.1%), and kanamycin (18.4%). Although isolates were susceptible to ciprofloxacin, 12 (2.1%) strains (one <i>S</i>. Infantis, one <i>S</i>. Manhattan, two <i>S</i>. Bareilly, two <i>S</i>. Blockley, two <i>S</i>. Heidelberg, two <i>S</i>. Minnesota, one <i>S</i>. Goldcoast, and one untypeable <i>Salmonella</i> strain) were resistant to the TGC cefotaxime, all of which harbored β-lactamase genes (<i>bla</i><sub>CMY-2</sub>, <i>bla</i><sub>CTX-M-15</sub>, <i>bla</i><sub>CTX-M-55</sub>, and <i>bla</i><sub>TEM-52B</sub>). Moreover, 1.3% (4/309) of <i>Salmonella</i> strains (three <i>S</i>. Infantis and one <i>S</i>. Manhattan strains) isolated from chicken products were resistant to cefotaxime and harbored <i>bla</i><sub>CMY-2</sub> or <i>bla</i><sub>TEM-52B</sub>. Thus, food workers may acquire TGC-resistant <i>Salmonella</i> after the ingestion of contaminated chicken products and further contaminate food products. |
| first_indexed | 2024-03-10T04:38:57Z |
| format | Article |
| id | doaj.art-cc7559af50324ba89ec4fefe8f403f7a |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-03-10T04:38:57Z |
| publishDate | 2021-12-01 |
| publisher | MDPI AG |
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| series | Antibiotics |
| spelling | doaj.art-cc7559af50324ba89ec4fefe8f403f7a2023-11-23T03:31:28ZengMDPI AGAntibiotics2079-63822021-12-011012154110.3390/antibiotics10121541Antimicrobial Resistance in <i>Salmonella</i> Isolated from Food Workers and Chicken Products in JapanYoshimasa Sasaki0Hiromi Kakizawa1Youichi Baba2Takeshi Ito3Yukari Haremaki4Masaru Yonemichi5Tetsuya Ikeda6Makoto Kuroda7Kenji Ohya8Yukiko Hara-Kudo9Tetsuo Asai10Hiroshi Asakura11Division of Biomedical Food Research, National Institute of Health Sciences, 3-25-26, Tonomachi, Kawasaki-ku, Kawasaki 210-9501, Kanagawa, JapanIncorporated Foundation Tokyo Kenbikyo-in, 1-100-38 Takamatsu-cho, Tachikawa 190-0011, Tokyo, JapanIncorporated Foundation Tokyo Kenbikyo-in, 1-100-38 Takamatsu-cho, Tachikawa 190-0011, Tokyo, JapanIncorporated Foundation Tokyo Kenbikyo-in, 1-100-38 Takamatsu-cho, Tachikawa 190-0011, Tokyo, JapanBML Food Science Solutions, Inc., 1549-7, Matoba, Kawagoe 350-1101, Saitama, JapanBML Food Science Solutions, Inc., 1549-7, Matoba, Kawagoe 350-1101, Saitama, JapanDepartment of Infectious Diseases, Hokkaido Institute of Public Health, Kita19 Nishi 12, Kita-ku, Sapporo 060-0819, Hokkaido, JapanPathogen Genomics Center, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, JapanDivision of Microbiology, National Institute of Health Sciences, 3-25-26, Tonomachi, Kawasaki-ku, Kawasaki 210-9501, Kanagawa, JapanDivision of Microbiology, National Institute of Health Sciences, 3-25-26, Tonomachi, Kawasaki-ku, Kawasaki 210-9501, Kanagawa, JapanDepartment of Applied Veterinary Science, The United Graduate School of Veterinary Science, Gifu University, 1-1, Yanagido, Gifu 501-1193, Gifu, JapanDivision of Biomedical Food Research, National Institute of Health Sciences, 3-25-26, Tonomachi, Kawasaki-ku, Kawasaki 210-9501, Kanagawa, Japan<i>Salmonella</i> is an enteric bacterial pathogen that causes foodborne illness in humans. Third-generation cephalosporin (TGC) resistance in <i>Salmonella</i> remains a global concern. Food workers may represent a reservoir of <i>Salmonella</i>, thus potentially contaminating food products. Therefore, we aimed to investigate the prevalence of <i>Salmonella</i> in food workers and characterize the isolates by serotyping and antimicrobial susceptibility testing. <i>Salmonella</i> was isolated from 583 (0.079%) of 740,635 stool samples collected from food workers between January and December 2018, and then serotyped into 76 <i>Salmonella enterica</i> serovars and 22 untypeable <i>Salmonella</i> strains. High rates of antimicrobial resistance were observed for streptomycin (51.1%), tetracycline (33.1%), and kanamycin (18.4%). Although isolates were susceptible to ciprofloxacin, 12 (2.1%) strains (one <i>S</i>. Infantis, one <i>S</i>. Manhattan, two <i>S</i>. Bareilly, two <i>S</i>. Blockley, two <i>S</i>. Heidelberg, two <i>S</i>. Minnesota, one <i>S</i>. Goldcoast, and one untypeable <i>Salmonella</i> strain) were resistant to the TGC cefotaxime, all of which harbored β-lactamase genes (<i>bla</i><sub>CMY-2</sub>, <i>bla</i><sub>CTX-M-15</sub>, <i>bla</i><sub>CTX-M-55</sub>, and <i>bla</i><sub>TEM-52B</sub>). Moreover, 1.3% (4/309) of <i>Salmonella</i> strains (three <i>S</i>. Infantis and one <i>S</i>. Manhattan strains) isolated from chicken products were resistant to cefotaxime and harbored <i>bla</i><sub>CMY-2</sub> or <i>bla</i><sub>TEM-52B</sub>. Thus, food workers may acquire TGC-resistant <i>Salmonella</i> after the ingestion of contaminated chicken products and further contaminate food products.https://www.mdpi.com/2079-6382/10/12/1541antimicrobial resistance<i>Salmonella</i>food workerchicken product |
| spellingShingle | Yoshimasa Sasaki Hiromi Kakizawa Youichi Baba Takeshi Ito Yukari Haremaki Masaru Yonemichi Tetsuya Ikeda Makoto Kuroda Kenji Ohya Yukiko Hara-Kudo Tetsuo Asai Hiroshi Asakura Antimicrobial Resistance in <i>Salmonella</i> Isolated from Food Workers and Chicken Products in Japan Antibiotics antimicrobial resistance <i>Salmonella</i> food worker chicken product |
| title | Antimicrobial Resistance in <i>Salmonella</i> Isolated from Food Workers and Chicken Products in Japan |
| title_full | Antimicrobial Resistance in <i>Salmonella</i> Isolated from Food Workers and Chicken Products in Japan |
| title_fullStr | Antimicrobial Resistance in <i>Salmonella</i> Isolated from Food Workers and Chicken Products in Japan |
| title_full_unstemmed | Antimicrobial Resistance in <i>Salmonella</i> Isolated from Food Workers and Chicken Products in Japan |
| title_short | Antimicrobial Resistance in <i>Salmonella</i> Isolated from Food Workers and Chicken Products in Japan |
| title_sort | antimicrobial resistance in i salmonella i isolated from food workers and chicken products in japan |
| topic | antimicrobial resistance <i>Salmonella</i> food worker chicken product |
| url | https://www.mdpi.com/2079-6382/10/12/1541 |
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