Synthesis and antitumor properties of some new N-(5-R-benzyl-1,3-thiazol-2-yl)-4,5-dihydro-1H-imidazole-2-carboxamides

Synthesis and antitumor properties of some new N-(5-R-benzyl-1,3-thiazol-2-yl)-4,5-dihydro-1H-imidazole-2-carboxamides

New N-(5-R-benzyl-1,3-thiazol-2-yl)-2-morpholin-4-yl-2-oxoacetamides have been prepared in good yields via the reaction of N-(5-R-benzyl-1,3-thiazol-2-yl)-2-chloroacetamides with sulfur and morfoline. These compounds react with ethendiamine to form a series of novel N-[5-R-benzyl)-1,3-thiazol-2-yl]-...

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Bibliographic Details
Main Authors: Volodymyr Ya Horishny, Iryna V Drapak, Taras I Chaban, Yuriy V Ostapiuk, Vasyl S Matiychuk
Format: Article
Language:English
Published: Universitas Gadjah Mada 2020-08-01
Series:Indonesian Journal of Pharmacy
Subjects:
organic synthesis
thiazole
imidazole
anticancer activity
Online Access:https://jurnal.ugm.ac.id/v3/IJP/article/view/596

Internet

https://jurnal.ugm.ac.id/v3/IJP/article/view/596

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