Extracellular Vesicular Transmission of miR-423-5p from HepG2 Cells Inhibits the Differentiation of Hepatic Stellate Cells

Extracellular Vesicular Transmission of miR-423-5p from HepG2 Cells Inhibits the Differentiation of Hepatic Stellate Cells

Liver fibrosis (LF) is a major cause of morbidity and mortality worldwide. Hepatic stellate cells (HSCs) are the primary source of extracellular matrix in the liver and their activation is a central event in LF development. Extracellular vesicles (EVs) are intercellular communication agents, which p...

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Bibliographic Details
Main Authors: Michal Safran, Rula Masoud, Maya Sultan, Irena Tachlytski, Chofit Chai Gadot, Ron Pery, Nora Balint-Lahat, Orit Pappo, Nahum Buzaglo, Ziv Ben-Ari
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cells
Subjects:
liver fibrosis
extracellular vesicles
exosomes
miRNA-423-5p
hepatic stellate cells
Online Access:https://www.mdpi.com/2073-4409/11/10/1715

Internet

https://www.mdpi.com/2073-4409/11/10/1715

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