Deep brain stimulation of the central thalamus restores arousal and motivation in a zolpidem-responsive patient with akinetic mutism after severe brain injury

Abstract After severe brain injury, zolpidem is known to cause spectacular, often short-lived, restorations of brain functions in a small subgroup of patients. Previously, we showed that these zolpidem-induced neurological recoveries can be paralleled by significant changes in functional connectivit...

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Bibliographic Details
Main Authors: Hisse Arnts, Prejaas Tewarie, Willemijn van Erp, Rick Schuurman, Lennard I. Boon, Cyriel M. A. Pennartz, Cornelis J. Stam, Arjan Hillebrand, Pepijn van den Munckhof
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-52267-1