Hsp70.1 carbonylation induces lysosomal cell death for lifestyle-related diseases

Hsp70.1 carbonylation induces lysosomal cell death for lifestyle-related diseases

Alzheimer’s disease, type 2 diabetes, and non-alcoholic steatohepatitis (NASH) constitute increasingly prevalent disorders. Individuals with type 2 diabetes are well-known to be susceptible to Alzheimer’s disease. Although the pathogenesis of each disorder is multifactorial and the causal relation r...

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Bibliographic Details
Main Authors: Tetsumori Yamashima, Takuya Seike, Shinji Oikawa, Hatasu Kobayashi, Hidenori Kido, Masahiro Yanagi, Daisuke Yamamiya, Shihui Li, Piyakarn Boontem, Eishiro Mizukoshi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Molecular Biosciences
Subjects:
Alzheimer’s disease
calpain-cathepsin hypothesis
hydroxynonenal
non-alcoholic steatohepatitis
type 2 diabetes
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.1063632/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2022.1063632/full

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