STAT3 is involved in IL-6-Mediated Downregulation of Hepatic Transporters in Mice

Interleukin (IL)-6 decreases hepatic expression of numerous transporters. Although IL-6 signaling occurs through STAT3, the extent of the involvement of the STAT3 signaling pathway has not been elucidated. PURPOSE: Our objective was to investigate whether IL-6-mediated effects occur through STAT3, a...

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Bibliographic Details
Main Authors: Walaa Ali Abualsunun, Micheline Piquette-Miller
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/30241