Structural analysis of viral infectivity factor of HIV type 1 and its interaction with A3G, EloC and EloB.
<h4>Background</h4>The virion infectivity factor (Vif) is an accessory protein, which is essential for HIV replication in host cells. Vif neutralizes the antiviral host protein APOBEC3 through recruitment of the E3 ubiquitin ligase complex.<h4>Methodology</h4>Fifty thousand V...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24586532/pdf/?tool=EBI |