Structural analysis of viral infectivity factor of HIV type 1 and its interaction with A3G, EloC and EloB.

Structural analysis of viral infectivity factor of HIV type 1 and its interaction with A3G, EloC and EloB.

<h4>Background</h4>The virion infectivity factor (Vif) is an accessory protein, which is essential for HIV replication in host cells. Vif neutralizes the antiviral host protein APOBEC3 through recruitment of the E3 ubiquitin ligase complex.<h4>Methodology</h4>Fifty thousand V...

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Bibliographic Details
Main Authors: Kauê Santana da Costa, Elcio Leal, Alberto Monteiro dos Santos, Anderson Henrique Lima e Lima, Cláudio Nahum Alves, Jerônimo Lameira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0089116&type=printable

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