Injury to the tunica media initiates atherogenesis in the presence of hyperlipidemia

Injury to the tunica media initiates atherogenesis in the presence of hyperlipidemia

Background and aimsFatty streaks initiating the formation of atheromatous plaque appear in the tunica intima. The tunica media is not known to be a nidus for lipid accumulation initiating atherogenesis. We assessed changes to the tunica media in response to a micro-injury produced in the pig aorta....

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Bibliographic Details
Main Authors: Hanane Belhoul-Fakir, Jiansha Wu, Yen L. Yeow, Gabrielle C. Musk, Helen Kershaw, Evan Ingley, Bichen Sophie Zhao, Christopher M. Reid, Christopher Lagat, Brian Evans, Peter L. Thompson, Michael L. Brown, Juliana Hamzah, Shirley Jansen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
atherogenesis
atherosclerosis
inflammation
vascular smooth muscle cell
atheroma
wall stress
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1152124/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2023.1152124/full

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