Self-assembly coupled to liquid-liquid phase separation.

Liquid condensate droplets with distinct compositions of proteins and nucleic acids are widespread in biological cells. While it is known that such droplets, or compartments, can regulate irreversible protein aggregation, their effect on reversible self-assembly remains largely unexplored. In this a...

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Bibliographic Details
Main Authors: Michael F Hagan, Farzaneh Mohajerani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-05-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010652