Microparticle alpha‐2‐macroglobulin enhances pro‐resolving responses and promotes survival in sepsis

Microparticle alpha‐2‐macroglobulin enhances pro‐resolving responses and promotes survival in sepsis

Abstract Incorporation of locally produced signaling molecules into cell‐derived vesicles may serve as an endogenous mediator delivery system. We recently reported that levels alpha‐2‐macroglobulin (A2MG)‐containing microparticles are elevated in plasma from patients with sepsis. Herein, we investig...

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Bibliographic Details
Main Authors: Jesmond Dalli, Lucy V Norling, Trinidad Montero‐Melendez, Donata Federici Canova, Hazem Lashin, Anton M Pavlov, Gleb B Sukhorukov, Charles J Hinds, Mauro Perretti
Format: Article
Language:English
Published: Springer Nature 2013-12-01
Series:EMBO Molecular Medicine
Subjects:
activation
innate immunity
lipoprotein receptor‐related protein 1
neutrophil
phagocytosis
Online Access:https://doi.org/10.1002/emmm.201303503

Internet

https://doi.org/10.1002/emmm.201303503

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