Cannabidiol-induced crosstalk of apoptosis and macroautophagy in colorectal cancer cells involves p53 and Hsp70

Abstract Although it has been established that cannabidiol (CBD), the major non-psychoactive constituent of cannabis, exerts antitumoral activities, the exact mechanism(s) via which tumor cells are killed by CBD are not well understood. This study provides new insights into the potential mechanisms...

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Bibliographic Details
Main Authors: Fei Wang, Ali Bashiri Dezfouli, Mohammad Khosravi, Wolfgang Sievert, Stefan Stangl, Melissa Schwab, Zhiyuan Wu, Katja Steiger, Hu Ma, Gabriele Multhoff
Format: Article
Language:English
Published: Nature Publishing Group 2023-08-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01578-9