Triggering of Eryptosis, the Suicidal Erythrocyte Death by Mammalian Target of Rapamycin (mTOR) inhibitor Temsirolimus

Triggering of Eryptosis, the Suicidal Erythrocyte Death by Mammalian Target of Rapamycin (mTOR) inhibitor Temsirolimus

Background/Aims: The mammalian target of rapamycin (mTOR) inhibitor temsirolimus is utilized for the treatment of malignancy. Temsirolimus is at least in part effective by triggering suicidal tumor cell death. The most common side effect of temsirolimus treatment is anemia. At least in theory, the a...

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Bibliographic Details
Main Authors: Abdulla Al Mamun Bhuyan, Hang Cao, Florian Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Phosphatidylserine
Eryptosis
Staurosporine
Oxidative stress
Calcium
Ceramide
Online Access:http://www.karger.com/Article/FullText/479398

Internet

http://www.karger.com/Article/FullText/479398

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